NeuroPEAK-PEA, is the Frau Pharma proposal based on Palmitoyletamide

Palmitoyletamide(PEA)is a natural product, present in several types of food(eggs, soy oil , peanuts etc) and is naturally produ- ced in the body.

Its phisiological role was studied and firstly described by the Nobel prize Rita Levi Montalcini in 1992. Extensively studied in the clinical practive with more than 5000 patients reported in the literature. No side euects are detected.

PEA acts at periphal level by inibiting the mastocites degranulation. Mastocites may be recruited at site of infiammation and via degranulation relase some pro-infiammatory citokines like TNF alpha.

PEA may work as neuroprotective in several chronic infiammation like:

  • premenstrual syndrome
  •  neuropatic diabetic pain
  •  lombosciatalgia
  • carpal tunnel syndrome
  • herpes zoster
  • sciatic pain
  •  fibromyalgia